
How Carnitine Improves Exercise Tolerance in Patients
In an Indian study, 47 patients with chronic stable angina were placed on a randomised, placebo-controlled trial using L-carnitine (2 g/day) for 3 months. Stress testing was carried out at the beginning and end of the treatment period.
Results show that the group had a statistically significant improvement in the exercise duration (7.8 pre-treatment, 8.6 minutes after treatment,) and in time needed for the ST changes to revert to baseline (7.2 pre-treatment, 5.7 min after treatment).
There were no benefits seen in time to onset for ST depression or ST score. The placebo treated group showed no significant changes in any parameter after placebo treatment, according to J Assoc Physicians India (2000;48:1050-1052).
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