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Researchers were surprised over recent test findings, which revealed that high cholesterol levels were not harmful to older people but still cautioned against prescribing cholesterol-lowering drugs to older people.

Researchers at the University of Hawaii studied 3,572 Japanese/American men between the ages of 71 and 93 years. The men had their cholesterol levels and numerous other parameters measured from 1991 to 1993.

By December 1996, there had been 727 deaths in the group. The researchers found that men with an average total cholesterol level of 5.99 mmol/L (235 mg/dL) had a 35 percent lower mortality rate (adjusted for age) than did men with an average cholesterol level of 3.85 mmol/L (150 mg/dL). The correlation between mortality and cholesterol levels was not changed after adjusting for other variables that could affect mortality.

The Lancet (Vol. 358, August 4, 2001, pp. 351-55) reported that the researchers also found that cholesterol levels tended to decline with age starting from an average of 5.0 mmol/L (195 mg/dL) in those aged 71 to 74 years to an average of 4.61 mmol/L (180 mg/dL) in those older than 85 years. They also observed that study participants who had maintained low cholesterol levels for 20 years or more had the highest mortality of all.