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Men's risk of prostate cancer may increase in tandem with the number of female sex partners they have had in their lifetime, according to the results of a new study. This finding supports the theory that prostate cancer may be triggered by an infectious agent, because men with more sex partners tend to have an increased risk of exposure to infection.

In the new study, the researchers looked at 753 men with prostate cancer and compared them with 703 men. The second group of men was the same age and was cancer-free. All were between the ages of 40 and 64.

Men who reported having gonorrhea had a slightly increased risk of prostate cancer, although other types of sexually transmitted diseases did not appear to increase risk significantly. There was no link between the number of male partners a man had and cancer, and the frequency of sex did not affect cancer risk.

Having two or more female sex partners during their teens, 20s, 40s and between age 50 to 64 increased men's risk of prostate cancer, compared with men who had sex with only one woman during each of these time periods, the investigators found. Also, men who had 30 or more sexual partners in their lifetime had an increased risk of more aggressive prostate cancer.

In contradiction of previous research, the study found that having sex for the first time at an earlier age was not associated with an increased risk of prostate cancer.

Past studies have found links between certain sexually transmitted diseases--particularly gonorrhea--and prostate cancer. Some studies have also linked prostate cancer to human papillomavirus, the cause of genital warts and a major contributor to cervical cancer in women. However, other studies have found no link between sexually transmitted diseases and prostate cancer.

However, the study could not prove that a higher number of sex partners was the actual cause of prostate cancer, according to the American Journal of Epidemiology 2001;152:1152-1158. More research is also needed confirm the results--and find a reason why they might be true.

Understanding how the prostate works and how it affects the aging male is of primary importance. In addition to prostate cancer, 50% of all male over 50 years have Benign Prostatic Hypertrophy ( BPH) that can be cured naturally.