Want to see our favorite hGH
supplement? Click here!
|
Smoking Mothers, HGH growth factors
Beratis NG, Varvarigou A, Makri M, Vagenakis AG.
Department of Paediatrics, University of Patras Medical School, General
University Hospital, Greece.
OBJECTIVE: Since maternal smoking causes fetal circulatory
abnormalities, as well as disturbances of the maternal endocrine
equilibrium, we measured the PRL, hGH and insulin-like growth factor-I (IGF-I)
concentrations in the cord and venous blood of neonates of smoking
mothers to determine whether or not the tobacco smoke affects the
endocrine status of the neonate. DESIGN: The above hormones were
measured in the cord blood of the newborns of both smoking and
non-smoking mothers. Also, PRL and hGH were determined at 24 and 72
hours after birth in newborns of both groups. PATIENTS: Fifty-three
newborns of smoking and 47 newborns of non-smoking mothers were
investigated. Seventeen of the newborns of the smoking and 21 of the
non-smoking mothers were preterm. The remainder were full-term.
MEASUREMENTS: PRL was measured with a solid-phase immunoradiometric
assay, hGH with a solid-phase two-site immunoradiometric assay and IGF-I
with a solid-phase radioimmunoassay after extraction with acid-ethanol.
RESULTS: The median value of PRL in the 17 preterm newborns of smoking
mothers was 4941 mU/I (range 1322-7230), whereas in the 21 preterm
newborns of non-smoking mothers it was 2013 mU/I (range 243-4740) (P =
0.0002). The median hGH value in the above subjects was 102.0 mU/I
(range 35.2-208.4) and 59.8 mU/I (range 11.6-134.2), respectively (P =
0.0039). The median IGF-I was 580.7 U/I (range 253.2-4851.1) and 530.6
U/I (range 239.6-3591.5), respectively (P = 0.429). In the 36 full-term
newborns of smoking mothers the median PRL value was 5171 mU/I (range
2074-7530), whereas in the 26 full-term newborns of non-smoking mothers
it was 5081 (range 244-6540) (P = 0.048). The median hGH was 69.6 mU/I
(range 42.3-280.0) and 32.2 mU/I (range 6.2-200.0), respectively (P =
0.0031). Also, the median IGF-I value was 926.3 U/I (range 348.5-5344.7)
and 462.1 U/I (range 250.2-1578.7), respectively (P = 0.0024). On the
3rd day the PRL in the preterm neonates of both smoking and non-smoking
mothers showed the same 16.5% drop, and thus the difference between the
groups was maintained. A similar reduction in the hormone levels was
observed in the full term neonates. CONCLUSIONS: The findings indicate
that the maternal tobacco-smoking causes disturbances of the endocrine
status of the fetus, as shown by the increased levels of PRL, hGH and
IGF-I, which are more pronounced between 30 and 37 weeks of gestation
than at term.
HGH
Renewals and Formulas
Click here to Buy HGH Human Growth
Hormone
HGH Index
Human Growth Hormone Antiaging
HGH ~ Anti Aging News
Human Growth Hormone (HGH) Antiaging Articles
More Aging & Health Resources (HGH)
Health Treatment, Resources, Articles
Human Growth Hormone (HGH) Antiaging Articles
Human Growth Hormone *HGH* Resources
Anti-Aging HGH Related Resource Articles
HGH Academy ~ Resources
HGH Academy ~ More Articles
HGH Growth Hormone Resources
Human Growth Hormones - HGH Resources
Aging Process
Human Growth Hormone Antiaging HGH Articles
HGH - Side Effects, Articles
Human Growth Hormone, HGH Enhancers
Human Growth Hormone Therapy -- HGH
HGH Related Articles on Antiaging
HGH Human Growth Hormone
The information on this website is not intended to cure,
prevent, or treat any disease. The information can be used for informational
purposes only. If you suspect you may have a medical problem, contact your
licensed health care practitioner. Please see our terms of use, disclaimer, and
privacy policy for more details.
Contact us: webmaster [at] hghacademy.com
|