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Growth and Metabolism - HGH

 

Adult Growth Hormone Deficiency at a glance

Growth deficiencies do not just affect children, they can be a significant problem for adults too. Until recently the effects of Growth Hormone Deficiency in adults were unknown. It is now recognized as a specific clinical syndrome with numerous physiological consequences, with effects on:

  • Changes in body composition, including central obesity;
  • Lipids in the blood;
  • Muscle strength;
  • Bone composition;
  • Exercise capacity an energy;
  • Cardiovascular risk; and
  • Psychological well-being (social isolation and depression).

In addition, there are also studies indicating that patients with hypo-pituitarism have an increased risk of mortality from cardiovascular disease, possibly attributable to their GH deficiency.

GH deficiency in adults can result from a pituitary or peri-pituitary tumor or as a direct result of the surgery/radiation used to manage these conditions. Less commonly GH deficiency in adults arises from a deficiency acquired in childhood.

Adult Growth Hormone Deficiency (AGHD) can be effectively treated recombinant human Growth Hormone. In August 2001, Serono received approval for the use of Saizen in the treatment of this condition in most European countries.

 






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